Erythropoietin or EPO is one of the key glycoprotein hormones, playing an all-important role of oxygen generation in blood. The role of Erythropoietin is difficult to overlook if you consider the complications that are likely to arise in case of lack of Erythropoietin production. This article attempts to provide an exhaustive insight into the role of Erythropoietin, especially with regards to the growth of erythroid.
Erythropoietin has widespread availability as a therapeutic agent derived from genetically engineered DNA made by recombining fragments of DNA from different organisms. In clinical terminology, this technology is referred to as recombinant DNA technology. It is basically applied to mammalian cell culture. Studies carried out to identify the role of Erythropoietin have yielded crucial information on the prospective treatment of anemia. It might be noted, however, that not all types of anemia can be treated by Erythropoietin. Anemia resulting from recurring kidney diseases is treatable by applying the recombinant DNA technology. It is also used in the treatment of carcinogenic ailments and a few other intricate complications such as cardiac failure.
Drugs made from Erythropoietin are applied to the patients suffering from chronic kidney ailments. These drugs are available worldwide and are approved by all the leading medical organizations. Patients who need to undergo dialysis are given special care and attention. Normally iron is given with Erythropoietin. Renal patients in the United States of America are normally given Epogen as an effective drug. In other countries, substitutes of Epogen are given to patients suffering from chronic kidney diseases.
The role of Erythropoietin is very important for the treatment of cancerous diseases as well. Drugs are mainly applied during the initial stages of cancer, especially when the patients undergo radiation therapy and chemotherapy.
The role of Erythropoietin is worth considering with regards to the production of red blood cells. EPO also acts as the fundamental growth factor of erythroid precursors. Note that homeostasis covers greater grounds than the elementary governing principles of the erythrocytic mass.
Some drugs made from Erythropoietin are officially declared harmful for individuals with chronic heart ailments. It's been seen that some drugs have the potential to increase blood circulation. Regular intake of such drugs may result in cardiac arrest.Many athletes have been found guilty of using banned Erythropoietin drugs.
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International tournaments such as Tour De France have often been marred by doping allegations. The role of Erythropoietin is very relevant in these contexts.
Flip through the pages of Pregnancyxl.com for more information on different hormones and their roles in human pregnancy.
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