In pregnancy related issues, the Lutenising Hormone plays a very crucial role. Commonly recognized as the LH, this hormone is also known as lutropin. It is synthesized and secreted by gonadotrophes in the pituitary gland anterior lobe. For proper functioning, the Lutenising Hormone cannot work alone. When it, both biologically and chemically, fuses up with another pituitary gonadotropin, follicle stimulating hormone (FSH), it works accordingly for proper reproductive functions.
The Lutenising Hormone works differently for both male and female body. Among females, during pregnancy period, a small rise of LH commences and it results in ovulation and when it comes to male, it excites the Leydig cell for proper production of testosterone. For male bodies, this hormone is also known as the Interstitial Cell Stimulating Hormone (ICSH).
Activity of Lutenising Hormone is essential for reproduction, in case of both male and female genders. Here activity of this hormone, for both men and women, will be discussed separately. In females, during their menstruation period, the FSH starts follicular growth and it affects granulosa cells. Consequently, there is rise in estrogen level to which Lutenising Hormone receptors respond. Maturing follicles of female reproductive organ produces, due to this hormonal flow, an increasing amount of estradiol. This hormone is essential for harmonizing for luteal function for the first two weeks. At the same time, LH plays main role to nourish thecal cells in the ovary. These
cells supply androgens and hormonal precursors for estradiol production.
In males, the LH casts its action over the Leydig cell of testis. This is the main reason for which production of testosterone happens. This male hormone is responsible for both endocrine and intratesticular activities. It also results in spermatogenesis, which means birth of sperms.
Over flow of this hormone causes several diseases to a human body. If flow of this hormone is natural, then no abnormal symptom is observed. But if there is either deficiency or high supply of this hormone, then various sorts of diseases can occur, such as: Premature menopause,Testicular failure, Castration,Swyer syndrome and Turner syndrome. Due to insufficient LH
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| supply, various types of other diseases will affect the human body, such as: Hypopituitarism, Hypothalamic suppression, Kallmann syndrome, Hyperprolactinemia, Gonadotropin deficiency and Eating disorder.
All these diseases cause serious physical ailments to human bodies. Not only that, hypo or hyper secretion of this hormone also causes serious harm to the embryo also and thats why the newborn child come on the earth with various types of physical deformities.
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