Ever wondered what triggers your excitement at any given point in time? You might have an answer in Thyroxine, a secretion of the thyroid gland. Thyroxine is a hormone which is formed by the combination of amino acid tyrosine and iodine. It is broken down to more complex structure before it gets stored in the follicle stems between thyroid cells. The entry of Thyroxine into the bloodstream is accompanied by its combination with another protein, plasma globulin. The main function of Thyroxine is to increase the number and activity of mitochondria in cells by bonding the DNA cells. The result is the increasing basal metabolic rate.
Effects of controlling Thyroxine:
Controlling Thyroxine can increase metabolic rate and even raise the rate of protein synthesis and breakdown. Combined, this leads to the increased activity of the endocrine system which becomes active in human body for duration of one month. The Thyroxine activity is actually triggered by thyrotropin, a substance released from the pituitary gland. The effect of thyrotropin is regulated by Thyroxine by feedback inhibition which means that high levels of thyroxine lower the rate of thyrotropin secretion. The synthetic Thyroxine is used for clinical treatment of thyroid gland deficiency diseases.
Structure of Thyroxine:
Before getting down to know about the structure of Thyroxine or 3,5,3',5'-tetra-iodothyronine (often abbreviated as T4), it is important to know that it is a form of thyroid hormones which is secreted by the follicular cells of the thyroid gland. T4 is carried in blood, with 99.95% of the secreted T4 being bound to protein, principally to thyroxine-binding globulin (TBG). To a comparatively lesser extent it also binds with transthyretin and serum albumin. The main work of T4 is to control the rate of metabolic processes in the body and thereby influence physical development of human body.
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Working of Thyroxine:
Considered a major hormone of human body, produced by the thyroid gland, Thyroxine plays an important role in regulating the metabolic functions of human body. The low production of Thyroxine leads to a condition known as Hypothyroidism. This mainly happens when the thyroid gland becomes naturally underactive. The underactivity of the gland may be also caused by radioiodine therapy or surgery for an overactive gland. Thyroxine is basically taken as replacement for deficiency for restoring normal metabolic activity of human body.
Pregnancyxl.com informs you about Thyroxine, to know more on the other hormones which play major role in Pregnancy, do keep browsing other pages of the site. Navigate your way through good health!
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